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About Oestrogel:

Oestrogel 0.06% Tube contains, 17B Estradiol (0.06%) as its main active ingredient. Which is a female sex hormone, applied directly on the skin. Used to treat menopause by reliving the menopausal symptoms.

About Estradiol Gel:

Estradiol is a type of Estrogen  which is a female sex hormone, produced in ovaries. There are many scenarios when body is unable to produce it in a sufficient quantity, causing menopause in women.  It is available in the form many brands such as:


Estradiol is prescribed in the cases where females are facing symptoms such as hot flashes, dryness in vagina and for the prevention of osteoporosis in postmenopausal women.  Many men and women use Oestrogel to treat some specific kind of Cancer


How Oestrogel works?

The main active ingredient is Estradiol or Oestradiol, which is the major sex hormone in female. When Oestrodiol Gel is applied on the skin, it is absorbed through the skin and flows in the blood. It is a steroid hormone produced inside the ovaries which develops the secondary sexual hormones and characteristics such as development of breast, regulation of menstrual cycle.

Estradiol also have other several actions such as metabolic processes such as fats and lipid.

Contents of Oestrogel pack:

Oestrogel is colorless, odourless and clear gel with the strength of 0.06% Oestradiol as the main ingredient. Ethanol, trolamine, carborner are present in the medication.

In one dose of Oestrogel there is 2.5g of gel. Containing 1.5mg of Estradiol.

Estradiol Gel usage for HRT:

Oestrogel is used in Hormone Replacement Therapy (HRT) as it contains oestrogen which is applied on the skin to tackle the lack of production of enough estrogen in the female. Estradiol is also used to treat menopause due to deficiency of oestrogen causing hot flashes, night sweats.

Using oestrogel in gender reassignment:

Oestrogel is can be used in gender reassignment from male to female. Oestrogel 0.06% contains 17B Estradiol which when taken, it develops the secondary sexual characteristics such as development of breast, regulation of menstrual cycles.


In which case you should not use this medication?

  • Bleeding genital
  • You are pregnant or planning to get pregnant.
  • Allergy with estradiol
  • Any Liver aliment


In which case you should not apply the medication?

You should not apply the Oestrogel if you are having the following issues:

  • If you are allergic to the externally applied creams and gels.
  • Allergic to Oestrogel
  • In past anyone in your family having carcinoma of the breast.
  • Having liver aliment
  • Genital bleedings


Any Side effects of Estradiol Gel?

The common side effect found are:

  • Itching around the applied region
  • Breast Tenderness
  • Chest Pain
  • Skin rashes
  • Headache


If you accidentally take high dose or double dose?

  • Breast Tenderness
  • Edema
  • Oedema
  • Abnormal abdominal pain
  • Adverse effect on Liver function


If you ever took high dose of the drug please contact emergency services immediately and seek medical help as soon as possible.


Interaction with the drug?

This is the list of medicines or medication which can decrease the effectiveness of the Oestrogel are as follows:

  • Anticonvulsants such as Carbamezapin, Phenobarbital, Phenytoin.
  • Anti-Infectives, such as Nevirapine, Efavirenz,  Rifampicin and Rifabutin.
  • Ritonavir and Nelfinavir for HIV.
  • Preparations containing St John’s Wort, such as Hypericum Perforatum.
  • Thyroid treatment medications such as Liothryonin, Liotrix, Levothryoxine etc.
  • Antifungal medicines like Clarithomycin, Erythomycin, Isoniazid, Telithromyocin etc.


Before taking any new medicine in the case when you are under the course of Oestrogel then you should consult your physician.


Risk of using Oestrogel:

When you take Estradiol externally, it can lead to some health risks such as:

  • Breast Cancer
  • Stroke
  • Chronic Chest Pain
  • Vein Thrombosis

Do not apply this medication if you are more than 65 years of age.


How to apply Oestrogel:

Apply one spatula of Oestrogel 0.06% which is 2.5g in amount, directly on the skin daily for at least 25-50 days or as long as your doctor has prescribed.  Avoid any kind of skin products on the area the medication applied to.

Do not take alcohol while under Oestrogel Medication.

Avoid applying strong cosmetics and soaps, as it can deter the effects of the medication.


I missed my dose?

If you have miss your dose take it immediately when you realise about it. Do not overdose or take double dose as it can be dangerous for you.


How to store Oestrogel?

Store the medicine in dark and cool place under 86 F or 30 C.



Ques: What is Estradiol?

Ans: Estradiol is a special type of estrogen found and secreted from Ovaries in female. Which is also called female sex hormone. When it is not produced in enough quantities can cause menopause.

Oestrogel is a transdermal gel which is applied to the skin that and it contains oestradiol, an active female hormone oestrogen that alleviates moderate to severe menopausal symptoms.

The gel is also used to help prevent postmenopausal bone loss (osteoporosis) and reduce risk of fracture.

To tacle these symptoms, estradiol is taken in the form medication. Estradiol is available in many brands such as:


Estradiol is prescribed in many cases such as Hot flashes, Vaginal Dryness and irritation. Oestrogel is sometimes is used as to treat breast cancer in women and in men to treat prostate cancer.

Very mild dose of estradiol in combination with progesterone hormone for oral contraceptive.


Ques: What are its common Side effects?

Ans: Nausea, Abdominal pain and bloating, vomiting, ankle swelling, absence of menstrual period,  swelling in limbs, muscle and stomach cramps and hair loss.

Ques: What’s the difference between estrogen and estradiol. Are the same as progesterone?

Ans: Estradiol is a natural estrogen which is produced in the ovaries in female. Progesterone is different female hormone.

Ques: Is Estradiol Valerate and Estradiol the same drug?

Ans: Estradiol valerate and estradiol are the same in nature.

Ques: How long do I need to take it?

Ans: It is dependent on the length of the Hormone Replacement Therapy. The duration of the treatment vary person to person. Your doctor can provide you the better feedback and timeline for it.

Ques: What all I should do under this drug?

Ans: You should take a balance diet. Do exercise on a daily basis. Live in healthy life style with less of pollution in the surroundings.

Ques: Does Oestrogel have odd or bad smell?

Ans: No, Oestrogel is odourless and colourless gel which is applied onto the skin directly. When it is applied, there is no irritation like side effects are found yet.

Ques: Can I use Oestrogel for transgender treatment?

Ans: Oestrogel contains 17B Estradiol (0.06%) which is an estrogen. It is usually taken when a female suffers from menopause. It works by applying 2.5 grams of gel which is measured by the spatula provided in the pack.

Oestrogel is a transdermal gel which contains oestrogen that is applied to the skin and it stimulates the development of secondary sexual characteristics of female such as development of breast , change in the function of metabolism, fat distribution on the female body and defining the body shape and size.


Additional Knowledge:

Before proceeding and applying Oestrogel onto your skin, you should so some research before going use and combat your post menopausal issues. Adequate diagnostic actions like endometrial sampling should be prescribed to rule out the occurrence of endometrial cancerous growths in case of persistent or abnormal vaginal spotting or bleeding.

Oestrogel is usually used for the HRT Treatment. Be careful and contact a qualified doctor before proceeding.

Additional information

1 Gel Of 80g

Generic Name : 17 β Estradiol
Generic for : Oestrogel
Manufactured By : Besins HealthCare, Belgium
1 Gel Of 80 gm